Cardiometabolic Outcomes in Multi-ethnic Physical Activity & Sedentary Behavior Study (COMPASS) NIH/National Heart, Lung, and Blood Institute; MPI: Drs. Robert Kaplan, Yasmin Mossavar-Rahmani, Vasan Ramachandran

This study explores whether a diverse primarily immigrant Hispanic/Latino population in the US differs from a mainly mainstream population in terms of the impact of physical activity on onset of diabetes. It is being conducted in the the Hispanic Community Health Study/Study of Latinos (HCHS/SOL) and the Framingham Heart Study (FHS) Third Generation and Omni Gen 2 (FHS Gen3/Omni2) cohorts. This approach not only increases generalizability of our findings to the total US population, but also helps us understand what is unique about Hispanics. An important question is how sedentary time can be harmful even among individuals who are physically active. The principal aims of the proposed study are: 1) To identify physical activity and sedentary behavior patterns associated with conversion to diabetes up to 12 years in 18 to 80 years old individuals by adding a second accelerometry measure to HCHS/SOL. We will examine influence of bout length and intensity of physical activity to define the dose-response relationships affecting diabetes risk. 2) To identify the relationship of moderate-vigorous physical activity, light physical activity and sedentary behavior with incident cardiovascular events and mortality, in order to define the magnitude of risks and dose-response for duration, intensity and bout length. 3) To investigate demographic and psychosocial correlates associated with 6+ year changes in patterns of physical activity and sedentary behavior in Hispanics/Latinos and non-Hispanics/Latinos with pre-diabetes.

Cardiovascular; Diabetes / Metabolic Syndrome; Minority Health
Principal Investigator:
Yasmin Mossavar-Rahmani, PhD, RD, CDN , Vasan Ramachandran
Robert C. Kaplan, PhD

Funding Agency:
National Heart Lung & Blood Institute
Start Date:
End Date:

Contact Person: Madeline Crespo-Figueroa
Contact Phone:

Associated division for this research project: Health Promotion and Nutrition Research